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Spiritualität & Sucht: Glaube als Ressource in der Alkoholismustherapie

Religiosität und Spiritualität stellen trotz eines Aufschwungs des Forschungsinteresses von Seiten der empirischen Psychologie noch immer ein Randgebiet im klinisch-psychiatrischen Feld dar. Die Sinnhaftigkeit der Integration von Spiritualität in die Therapie des Alkoholismus, als einer der häufigsten psychischen Erkrankungen, erscheint vor allem durch die Erfolge der Anonymen AlkoholikerInnen bestätigt. Wenig empirisches Datenmaterial wurde allerdings gesammelt, um die stützende Funktion religiös-spiritueller Inhalte im Erleben der Betroffenen wissenschaftlich zu evaluieren.

Test–Retest reliability of a lifetime drug use questionnaire

By adopting the investigational principle of the Lifetime Drinking History (LDH) interview, we developed a Lifetime Drug Use (LDU) Questionnaire to assess the amount and frequency of lifetime drug consumption.

Spiritualität als Forschungsgegenstand der klinischen Religionspsychologie

Kein Abstract vorhanden.

Reduced dopamine D3 receptor expression in blood lymphocytes of smokers is negatively correlated with daily number of smoked cigarettes: a peripheral correlate of dopaminergic alterations in smokers

The mesolimbic dopaminergic system is known to mediate rewarding effects of nicotine administration, and dysfunctions of this system may underlie failure to stop cigarette smoking. Expression of dopamine receptors in peripheral blood lymphocytes (PBLs) has been indicated as a peripheral correlate of brain status. Dopamine receptor D(3) (DRD3) and D(4) (DRD4) mRNA expression in PBLs was measured by real-time polymerase chain reaction in smokers (n=26) and former smokers (n=14), compared with nonsmoking control subjects (n=35).

Reduced dopamine D4 receptor mRNA expression in lymphocytes of long-term abstinent alcohol and heroin addicts

Aim: It has been repeatedly suggested that dopamine receptor expression in peripheral blood lymphocytes reflects, to some extent, brain status. The aim of the present study was to investigate dopamine receptor expression in peripheral blood lymphocytes of long-term abstinent alcohol and heroin addicts against the background of the hypothesis, that a persisting dysfunction of the dopaminergic system contributes a biological cause to the chronic character of addiction.

Dopamine receptor D3 mRNA expression in human lymphocytes is negatively correlated with the personality trait of persistence

It has been proposed that neurotransmitter receptor expression in peripheral immune cells reflects expression of these receptors in the brain. To test this "peripheral marker hypothesis", we compared mRNA expression of the dopamine receptors D3 (DRD3) and D4 (DRD4) in peripheral blood lymphocytes (PBL) to personality traits assessed with the Temperament and Character Inventory (TCI) in 50 healthy and unmedicated Caucasian individuals. A shared variance of at least 17% (p=0.016) between DRD3 mRNA expression in PBL and the personality trait of persistence was found.

Test-Retest Reliability of a Lifetime Drug Use (LDU) Questionnaire

By adopting the investigational principle of the Lifetime Drinking History (LDH) interview, we developed a Lifetime Drug Use (LDU) Questionnaire to assess the amount and frequency of lifetime drug consumption.

Development of a Lifetime Alcohol and Polydrug Use (LAPU) Questionnaire

By adopting the investigational principle of the Lifetime Drinking History (LDH) interview, we developed a Lifetime Drug Use (LDU) Questionnaire to assess the amount and frequency of lifetime drug consumption.

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