Background Nutrition with antioxidant capacity can have important effects on the proinflammatory status of individuals. Fruit and vegetable consumption was been reported to influence proinflammatory gene expression. Patients with fructose/lactose intolerance represent a group of controlled dieters. The current study assessed the potential difference of proinflammtory gene expression between fructose/lactose intolerant patients and healthy controls. Methods In total 71 subjects were investigated.