Background: Previous research has linked insecure attachment styles and borderline personality organization to Substance Use Disorder (SUD). However, it still remains unclear whether those impairments apply to different kinds of SUDs to the same extent.
The relationship between substance use disorders (SUD) and brain deficits has been studied extensively. However, there is still a lack of research focusing on the structural neural connectivity in long-term polydrug use disorder (PUD). Since a deficiency in white matter integrity has been reported as being related to various parameters of increased psychopathology, it might be considered an aggravating factor in the treatment of SUD.